1V-LSD (1-valeroyl-lysergic acid diethylamide), or “Valerie,” in 10 mcg pellets is specifically designed for microdosing. Unlike the 150 mcg or 225 mcg doses used for full psychedelic “trips“. A 10 mcg dose intends to be “sub-perceptual”—meaning you should not experience hallucinations or a significant shift in reality.

The Microdose Profile: 10 mcg

In the world of lysergamides, 10 mcg is consider a standard microdose. Because 1V-LSD is a prodrug and has a higher molecular weight than LSD-25, this dose is roughly equivalent to 7–8 mcg of traditional LSD.

• Sub-perceptual: At this level, you should not see “breathing” textures or tracers. If you do, the dose is too high for a true microdose.

• Metabolism: The “Valeroyl” group makes the onset slightly slower than other analogs. You may not notice any subtle shifts for 90 to 120 minutes.

• Duration: Even at 10 mcg, the substance remains in your system. While the “active” window is subtle, it can affect sleep patterns for up to 12–15 hours.

• Microdose Pellets: Usually contain 10 µg of the active compound and are marketed for microdosing regimens.
• Standard Pellets: Often contain 150 µg of the substance, a higher nominal dose than standard LSD tabs to compensate for its lower mass-relative potency.

• Structure: It differs from classic LSD by the addition of a valeroyl (pentanoyl) group attach to the nitrogen atom of the indole ring.
• Potency: Animal studies (measuring the mouse head-twitch response) indicate that 1V-LSD has approximately one-third the potency of LSD.
• Equivalency: A 150 µg dose of 1V-LSD is generally reported to produce effects comparable to roughly 100 to 120 µg of 1P-LSD or 1cP-LSD.

Effects and Duration of 1V-LSD Pellets

• Psychological: Altered states of consciousness, visual hallucinations, synesthesia, and intensified emotional processing.
• Physical: Pupil dilation (mydriasis), increased heart rate, elevated blood pressure, and changes in body temperature regulation.
• Duration: User reports vary, with some noting a delayed onset and a duration extending past 10–12 hours, while others report a compressed timeline of 6–8 hours.